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Medicine Miscellaneous 7eab82f9

Which of the following investigation would be diagnostic of cystic fibrosis?

A
Deficiency of the enzyme mucinase
B
High sweat chloride content
C
Alpha-1 aldolase deficiency
D
Increased copper excretion in urine
High-Yield Explanation
A sweat test measures the amount of chloride, a pa of salt, in Sweat. It is used to diagnose cystic fibrosis (CF). People with CF have a high level of chloride in their sweat. CF is a disease that causes mucus build-up in the lungs and other organs. It damages the lungs and makes it hard to breathe Ref Davidson 23rd edition pg 944

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