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Physiology General 7e63f678

Blood brain barrier is formed by which of the following cells?

A
Schwann cells
B
Oligodendrocytes
C
Astrocytes
D
Microglia
High-Yield Explanation
Oligodendrocytes and Schwann cells are involved in myelin formation around axons in the CNS and peripheral nervous system, respectively. Astrocytes, which are found throughout the brain, are of two subtypes. Fibrous astrocytes, which contain many intermediate filaments, are found primarily in white matter. Protoplasmic astrocytes are found in gray matter and have a granular cytoplasm. Both types send processes to blood vessels, where they induce capillaries to form the tight junctions making up the blood-brain barrier. Ref: Ganong's Review of Medical Physiology 23rd edition, Chapter 4.

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