Ability of stein cells to cross barrier ofdifferentiation to transform into a cell of another lineage expressing the molecular characteristics of different cell type with the ability to perform the function of the new cell type is referred as:

Trans differentiation Transdifferention is defined as:- The change of a cell or tissue from one differentiated state to another. The differentiation of a tissue specific stem cell into another type of cell as for example a bone marrow stem cell differentiating into a neuron. Dedifferentiation It is a cellular process commonly believed to be uniquely available to lower life forms such as worms and amphibians in which a paially or terminally differentiated cell reves to an earlier developmental stage. Cells in cell culture can lose propeies they originally had such as protein expression or change shape. This process is also termed dedifferentiation. Dedifferention can also be observed in some tumour e.g. dedifferentiated liposarcomas which will show more immature areas in an otherwise differentiated liposarcoma. Regression of a specialized cell or tissue to a simpler, more embryonic, unspecialized.form i.e. a reversal of cell development so that differentiation that had occurred previously is lost and the cells become more generalized in structure. Red iffere ntiation A process by which a group of once differentiated cells return to their original specialized form.