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Microbiology Immunology 7e3f77c4

All are true regarding agammaglobulinemia except -

A
Loss of germinal centre in lymph node
B
Normal coical lymphocytes
C
Normal coical lymphocytes in paracoex and medulla
D
Decreased red pulp in spleen
High-Yield Explanation
In agammaglobulinemia all classes of immunoglobulins are grossly depleted in the serum. Tonsils & Adenoids are atrophic. Lymph node biopsy reveals depletion of cepls of bursa dependent areas. Plasma cells and germinal centres are absent even after antigenic stimulation. There is marked decrease in the poion of B cells in circulation. Ref: Ananthanarayan & Panikers textbook of microbiology 9th edition pg.no. : 171,172

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