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Pathology General 7e00897f

What is the best prognostic indicator of multiple myeloma at the time of diagnosis ?

A
Number of myeloma cells in the marrow
B
Beta 2 microglobulin
C
Alkaline phosphatase level
D
Hypercalcemia
High-Yield Explanation
Ans. is 'b' i.e., Beta-2 Microglobulins o Serum /32 microglobulin is the single most powerful predictor of survival and can substitute for staging.P2 Microglobulin level :< .004g/L Median survival of 43 months.> .004 g/L Median survival of only 12 months.

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