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Pathology Immune Deficiency Diseases 7dbbfdf4

Nitro-blue tetrazolium test is done for?

A
Chronic glomerulonephritis
B
Chronic granulomatous disorder
C
Acute granulomatous disease
D
Chediak Higashi syndrome
High-Yield Explanation
Ans. (b) Chronic Granulomatous disorderRef: Robbin's pathology 9th ed. /237-238Nitro blue tetrazolium is used in a diagnostic test, particularly for chronic granulomatous disease. When there is an NADPH oxidase defect, the phagocyte is unable to make reactive oxygen species or radicals required for bacterial killing. As a result, bacteria may thrive within the phagocyte. The higher the blue score, the better the cell is at producing reactive oxygen species.

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