A child was diagnosed as a case of pauci–immune crescentic glomerulonephritis. The treatment to be given in this child is –
High-Yield Explanation
Panel-immune glomerulonephritis
Pauci-immune glomerulonephritis is defined as the lack of anti-GBM antibodies or immune complex.
It is a type of rapidly progressive glomerulonephritis.
Causes are :-
Idiopathic renal-limited crescentic glomerulonephritis (ANCA associated).
Microscopic PAN
Microscopic polyangitis
Wegner's gramdomatosis
It is treated aggressively with glucocorticoids with or without cyclophosphamide or azathioprine