Myaesthenia gravis is associated with:

Answer is D (Decreased Myoneural junction transmission): The primary defect in Myaesthenia gravis is decreased transmission across the myoneural junction due to decrease in the number of Acetylcholine receptors. The fundamental defect is Myaesthenia gravis is a decrease in the number of Acetylcholine Receptors at the postsynaptic muscle membrane, which results in decreased efficiency of neuromuscular transmission' -- Harrison