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Pharmacology Anti Microbial 7d2ba288

Single-dose mebendazole is effective in treatment of

A
Enterobius vermicularis
B
Ankylostoma duodenale
C
Ascaris lumbricoides
D
All of the above
High-Yield Explanation
Ans. a (Enterobius vermicularis) (Ref. Nelson paediatrics 18th/ p. 1450; KDT Pharmacology 6th/809)Enterobius: 100 mg single dose mebendazole, repeated after 2-3 weeks.Round worm:Hookworm:Mebendazole 100 mg twice a day for 3 consecutive days.Whipworm:NO fasting/purging/other preparation needed.Enterobius vermicularis (pinworm) infection; Drug of choice (adult as well pediatric dosage)# Pyrantel pamoate 11 mg/kg base once (max 1 g); repeat in 2 wk OR# Mebendazole 100 mg once,repeat in 2 wk OR# Albendazole 400 mg once; repeat in 2 wk.Ascariasis (Ascaris lumbricoides. roundworm); Drug of choice# Albendazole 400 mg once OR# Mebendazole 100 mg bid x 3 days or 500 mg once OR# Ivermectin 150-200 microg/kg once

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