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Pathology G.I.T. 7cf99676

Histopathological finding of gluten hypersensitivity is?

A
Crypt hyperplasia
B
Increase in thickness of the mucosa
C
Distal intestine involvement
D
Villous hypertrophy
High-Yield Explanation
Ans. is 'a' i.e., Crypt hyperplasia Histopathological findings of gluten sensitivity enteropathy* Villous atrophy and Crypt hyperplasia with decrease in villus: crypt ratio.* Loss of microvilli brush border.* Inflammatory cells are present in lamina propria : plasma cells, macrophages, lymphocytes, eosinophils and mast cells.* One of the characteristic feature is that overall mucosal thickness remains same (as villous atrophy is compensated by crypt hyperplasia).* Mainly proximal intestine is involved.

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