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Pharmacology General 7cee84e8

A drug given for metoclopramide induced dystonic reaction is :

A
Pheniramine
B
Promethazine
C
Chlorpromazine
D
Prochlorperazine
High-Yield Explanation
"Acute muscle dystonia caused by antiemetic-antipsychotic drugs is promptly relieved by parenteral promethazine or hydroxyzine." This is based on the central anticholinergic action of the drugs. Promethazine is a first-generation anti-histaminic which has a maximum penetration of blood-brain barrier and maxi­mum anticholinergic activity.

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