Mechanism of action of progesterones in the medical management of endometriosis is?
High-Yield Explanation
Progesterones act by exeing an anti estrogenic effect and their continuous administration causes decidualisation and endometrial atrophy. The treatment over a period of 6 - 9 months produces a state of pseudopregnancy which ultimately causes regression of disease. It has no effect on ovulation Progestins used commonly are: Norethisterone Dydrogesterone Medroxyrogesterone acetate Mirena IUCD Dienogest