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Pathology Intestinal Polyps, Colon & Anal Cancer 7cdf5a39

Histological finding of solitary rectal ulcer syndrome is:

A
Thick collagen band under endothelial layer
B
Intraepithelial collection of lymphocytes
C
Crypt hypoplasia
D
Increased muscle layer proliferation
High-Yield Explanation
Mucosal prolapse syndrome/ solitary rectal ulcer syndrome d/t chronic mechanical stimulation Recognized in prolapsing colostomies, inflammatory polyps, solitary ulcer or prolapsing hemorrhoid at the site of rectum - Microscopically, there is Intercryptal erosion, hyperplasia of crypts (some have peculiar diamond shape). Obliteration of lamina propria by fibroblasts, elastin & smooth muscle cells from muscularis mucosae Reduction in number of lymphocytes & plasma cells Thickening of the muscularis mucosa with splaying of its fibers.

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