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Physiology Misc. 7cc28cb2

Growth hormone secretion is decrease by all except

A
Glucose
B
Stressful stimuli
C
Sleep
D
Somatostatin
High-Yield Explanation
(C) Sleep > Stressful stimuli also increases GH levels.> Whereas REM sleep decreases GH secretion, but going to sleep increases it.# Stimulators of growth hormone (GH) secretion include: peptide hormones; GHRH (somatocrinin) through binding to the growth hormone-releasing hormone receptor (GHRHR) Ghrelin through binding to growth hormone secretagogue receptors (GHSR) Sex hormones; increased androgen secretion during puberty (in males from testis and in females from adrenal cortex); estrogen> Inhibitors of GH secretion include: GHIH (somatostatin) from the periventricular nucleus circulating concentrations of GH and IGF-1 (negative feedback on the pituitary and hypothalamus) hyperglycemia; glucocorticoids; dihydrotestosterone> in addition to control by endogenous and stimulus processes, a number of foreign compounds (xenobiotics such as drugs and endocrine disruptors) are known to influence GH secretion and function.

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