Most common site of carcinoma esophagus is:

Answer is C (Lower 1/3rd) The lower third of the esophagus is the most common site of esophageal cancer and accounts for about 50% of all esophageal cancers. `About 15% of esophageal cancers occur in the upper third of esophagus (cervical esophagus), 35% in the middle third of esophagus and 50% in the lower third' - Harrison 16th/524 Site of esophageal cancer (All histological types) % of total Upper 1/3' 15% Middle 1/3rd 35% Lower 1/3'd 50% Note: The most common site of squamous cell (histological subtype) is middle 1/3 of esophagus The most common site of adenocarcinoma (histological subtype) is lower 1/3rd of esophaguse.