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Medicine General 7bdb4aa5

Dent's disease is characterized by all except

A
Chloride channel defect
B
Males are affected
C
Nephrolithiasis
D
Defect in limb of Loop of Henle
High-Yield Explanation
Answer- D. Defect in limb of Loop of HenleDent's disease refers to heterogenous group of X-linked disorders. It b characterized by manifestations of proximal tubule dysfunction (PT) dysfunction associated with hypercalciuria nephrolithiasis, nephrocalcinosis and progressive renalfailureThese features are found in males only.mutation in gene encoding CLS-S, a Voltage gated Chloide channel.

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