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Pathology Interstitial lung diseases 7b3c3dfc

Which of the following statement are not related to pathogenesis of idiopathic pulmonary fibrosis?

A
Smoking
B
Age less than 20 years
C
Loss of function mutation in TE and TERC gene
D
Mutations in genes encoding components of surfactant
High-Yield Explanation
Idiopathic pulmonary fibrosis aka Cryptogenic fibrosing alveolitis It is characterized by recurrent alveolar epithelial injury. SMOKING is one of the most impoant etiological factor. Seen in patient more than 50 years It is also associated with altered activity of surfactant. Histopathological Hallmark -Usual interstitial Pneumonia Rx-Lung transplant

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