All of the following syndromes are associated with AML except –

Etiology of AML Hereditary - Down syndrome, Klinefelter syndrome, Patau syndrome, Fanconi anemia, Bloom syndrome, Ataxia telangiectasia, Kotsman syndrome. Radiation Chemical and other exposure Benzene, smoking, ethylene oxide, paint, herbicide and pesticides. Drugs Alkalating agents, Topoisomerase II inhibitors, Chloramphenicol, phenylbutazone and less commonly chloroquine, thethoxypsoralen can result in bone marrow failure that may result in AML. Note : Turner syndrome also causes leukemia - Nelson 18th/e p. 2117 table 495.1