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Gynaecology & Obstetrics General 7afb4038

Mifepristone may be used for all of the following, EXCEPT:

A
Threatened Aboion
B
Ectopic pregnancy
C
Fibroids
D
Molar Pregnancy
High-Yield Explanation
Mifepristone is a antiprogestin which binds to the progesterone receptors and thus prevents the action of progesterone. The administration of mifepristone is usually followed by a synthetic prostaglandin analogue thus effectively brings about aboion. Threatened aboion is a condition diagnosed clinically by the bleeding occurring in the early pregnancy and by the presence of a definite hea sound and a hematoma (sub-chorionic/marginal sinus/retroplacental) ultrasonographically. Every attempt must be taken to preserve the pregnancy in threatened aboion by applying expectant management. Use of a aboificient is not included in the management of threatened aboion. Ref: Clinical applications of mifepristone (RU 486) By Leslie Z. Benet, Molla S. Donaldson, Pages 3-19 ; Bleeding During Pregnancy: A Comprehensive Guide By Eyal Sheiner, Page 33.

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