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Pathology Hemodynamics 7ae94a49

Lacunar Reed Sternberg cell is found in which type of Hodgkin's lymphoma?

A
Mixed cellularity
B
Lymphocyte rich
C
Nodular sclerosis
D
Lymphocyte depleted
High-Yield Explanation
Ref: Harsh Mohan, 7th ed. pg. 350Type of Hodgkin's lymphomaNodular sclerosisMost common type of Hodgkin lymphomaLacunar Reed-Sternberg cell variants in a mixed inflammatory background; broad sclerotic bands of collagen usually also presentCD15+, CD30+ Reed- Sternberg cellsMost common in young adults, often arises in the mediastinum cervical lymph nodesMixed celiularity typeSecond most common form of Hodgkin lymphomaFrequent classic Reed-Sternberg cells in a mixed inflammatory backgroundCD15+, CD30+, Reed-Sternberg cellsMost common in men, more likely to present at advanced stages than the nodular sclerosis type EBV+in 70% of cases

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