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Biochemistry Vitamins and Minerals 7ad9dbcd

In vitamin B12 deficiency, folate is trapped in the form of

A
Formyl THFA
B
Methenyl THFA
C
Methyl-THFA
D
Methylene-THFA
High-Yield Explanation
Methylation of homocysteine to methionine is the only way of regeneration of active THFA from methyl THFA. Methionine synthase reaction requires methyl cobalamin. So, deficiency of methyl-B12 leads to trapping of THFA in less utilised methyl-THFA - phenomenon known as folate trap.

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