A 23-year-old female has prolonged complaints diarrhea, flatus and pain in abdomen. Her appetite is preserved still she is experiencing weight loss. Physical examination is within normal limit. Small intestinal biopsy reveals- villous atrophy lymphocytic infiltration of lamina propria with crypt hyperplasia. She was put on a special diet and she improved. How can the above condition be differentiated from Whipple disease?