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Microbiology General 7ab52697

All of the following statements about staphylococcus aureus are true, Except -

A
Most common source of infection is cross infection from infected people
B
About 30% of general population is healthy nasal carriers
C
Epidermolysis and TSS toxin are superantigens
D
Methicillin resistance is chromosomally mediated
High-Yield Explanation
Most common source of infection of staph. aureus is an endogenous infection from individuals own colonizing strains. Most individuals who develop staph. aureus infections do so with their own colonizing strains. Most common route of infection is skin. In hospital infections (nosocomial infections), transmission of staphylococci results most frequently from transient colonization of hands of hospital personnel, who then transfer strains from one patient to another. Staphylococci are part of normal human bacterial flora with about 30% of the general population being nasal carriers and another 10% carrying it on the perineal skin. Option 'c' is partially correct as TSS toxin (TSST) is a superantigen, but Epidermolysis is not a superatigen. Methicillin resistance of staphylococcus aureus is chromosomally mediated and is due to the production of PBP2a.

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