All of the following statement are true regarding CNS infection, except :
High-Yield Explanation
CNS manifestation of CMV :
– CMV rarely cause CNS infection.
– Two forms of CMV encephalitis are seen :
Resemble HIV encephalitis and present as progressive dementia.
Ventriculoencephalitis - Characterized by cranial nerve deficit, nystagmus and ventriculomegaly.
– In immunocompromised patient, CMV can also cause subacute progressive polyradiculopathy. Nowhere is given that CMV can cause temporal lobe infarction : Hence answer is OPTION 2
Other options :
Subacute sclerosing pan encephalitis:
– It is a rare chronic progressive demyelinating disease of CNS associated with a chronic permissive infection of brain tissue with measles virus.
Progressive Multifocal leucoencephalopathy:
– Progressive disorder characterised pathologically by multifocal areas of demyelination of varying size distributing throughout the CNS caused by JC virus.
Spongiform encephalopathy:
– Caused by prion infection; HIV infection.