Large way vegetation are characteristic of-

Subacute endocarditis refers to infections by organisms of low virulence involving a previously abnormal hea, especially scarred or deformed valves. The disease typically appears insidiously and--even untreated--follows a protracted course of weeks to months; most patients recover after appropriate antibiotic therapy. characteristically results in bulky, friable vegetations composed of necrotic debris, thrombus, and organisms. The aoa, aneurysmal sacs, other blood vessels and prosthetic devices also can become infected. (Robbins Basic Pathology,9th edition,pg no394.)