Howel Jolly bodies seen in peripheral smear after

(A) Splenectomy > Howell-Jolly bodies are histopathological findings of basophilic nuclear remnants (clusters of DNA) in young erythrocytes during the response to severe hemolytic anemia, megaloblastic anemia, splenectomy, or due to a damaged spleen.> They can be present in conditions such as hyposplenism, hereditary spherocytosis, sickle cell anemia and myelodysplastic syndrome (MDS).