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Physiology General 798707c9

Which of the following actions does aldosterone secretion from the adrenal gland regulate in the kidney?

A
Exchange of K+ for Na+ in the distal convoluted tubule
B
Exchange of Na+ for K+ in the distal convoluted tubule
C
Exchange of K+ for Na+ in the proximal convoluted tubule
D
Exchange of Na+ for K+ in the proximal convoluted tubule
High-Yield Explanation
The distal convoluted tubule (DCT) in the kidney coex functions to reabsorb Na+ and secrete K+. This is regulated by the adrenal hormone, aldosterone, as stimulated by angiotensin II, which will increase reabsorption of Na+ and secrete K+. The DCT also functions in the continuation of bicarbonate ion reabsorption with hydrogen ion secretion. The terminal poion of the DCT is sensitive to antidiuretic hormone (ADH) from the neurohypophysis, which acts to increase the permeability of the tubule to water, resulting in concentrating the urine. Ref: Barrett K.E., Barman S.M., Boitano S., Brooks H.L. (2012). Chapter 20. The Adrenal Medulla & Adrenal Coex. In K.E. Barrett, S.M. Barman, S. Boitano, H.L. Brooks (Eds), Ganong's Review of Medical Physiology, 24e.

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