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Pharmacology General 7927b2d0

All of the following are Beta-lactamase inhibitors except: March 2005

A
Clavulanic acid
B
Aztreonam
C
Sulbactam
D
Tazobactam
High-Yield Explanation
Ans. B: Aztreonam Monobactams-Unlike other beta-lactams, the monobactam contains a nucleus with no fused ring attached. Thus, there is less probability of cross-sensitivity reactions. Aztreonam Tigemonam Nocardicin A Tabtoxinine-beta-lactam. Beta-lactamase inhibitors: Although they exhibit negligible antimicrobial activity, they contain the beta-lactam ring. Their sole purpose is to prevent the inactivation of beta-lactam antibiotics by binding the beta-lactamases, and, as such, they are co-administered with beta-lactam antibiotics. Clavulanic acid Tazobactam Sulbactam.

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