Full 2L QBank
Pathology Liver & Biliary Tract 78ca5c9b

A 23-year-old man has noted a yellow color to his sclerae for the past 2 weeks. On physical examination, he has generalized jaundice. He has the physique of a bodybuilder. Laboratory studies show serum total bilirubin, 5.6 mg/dL; ALT, 117 U/L; AST, 103 U/L; alkaline phosphatase, 148 U/L; albumin, 5.5 g/dL; and total protein, 7.9 g/dL. Which of the following substances is he most likely to be using?

A
Acetaminophen
B
Anabolic steroid
C
Chlorpromazine
D
Ethyl alcohol
High-Yield Explanation
Anabolic-androgenic steroids are injected for the purpose of increasing muscle mass to enhance athletic performance. Because performance is primarily correlated with skill and training, the potential gain from muscle mass is problematic, particularly in view of the deleterious effects, such as hepatic cholestatic hepatitis. Acetaminophen can produce hepatic necrosis, but icterus is less likely. Chlor- promazine is more likely to produce pure cholestasis as an idiosyncratic (unpredictable) reaction. Ethanol can produce steatosis, and in excess, the AST is often higher than the ALT. Isoniazid may produce hepatic necrosis in persons treated for tuberculosis.

Related Pathology MCQs

Practice 2,00,000+ NEET PG Questions Free

Timed mock tests, mistake queue analytics, audio lectures & zero attempt limits on i❤️Exams.

Start Free Mock Test Now