Mucoepidermoid carcinoma arises form -
High-Yield Explanation
Mucoepidermoid carcinomas are composed of variable mixtures of squamous cells, mucus-secreting cells, and intermediate cells.
"The low-grade mucoepidermoid carcinoma is composed of largely mucin-secreting cells, whereas in high-grade tumors, the epidermoid cells predominate."- Schwartz
They are the most common malignant tumors of the salivary glands.
Treatment
The primary t/t of all salivary malignancy is surgical excision:
for parotid malignancies-
Superficial parotidectomy with preservation of CN VII.
Total parotidectomy with nerve preservation if deep lobe is involved.
for other salivary gland -
Enbloc removal of the involved gland
Neck dissection for lymph nodes is done
clinically palpable nodes
for high grade malignancies
Radiation therapy is used postoperatively for specific indications
high grade histology
presence of extraglandular disease
perineural invasion
direct invasion of regional structure
regional metastasis