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Pharmacology Mycobacterial Diseases (TB, Leprosy and MAC) 786d78ee

Which of the following anti TB drugs acts on extracellular organisms and is bactericidal drug?

A
Isoniazid
B
Streptomycin
C
Rifampicin
D
Ethambutol
High-Yield Explanation
Streptomycin is the only anti-TB drug which acts on extracellular organisms and is bactericidal. All first line antitubercular drugs are bactericidal except ethambutol which is bacteriostatic. Impoant points about first line ATT: Drug Action Hepatotoxic Bacteria Inhibited Isoniazid CIDAL Yes Both Rifampicin CIDAL Yes Both Pyrazinamide CIDAL Yes Intracellular Ethambutol STATIC No Both Streptomycin CIDAL No Extracellular

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