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Microbiology Mycology 786b450a

Best stain for cryptococcal capsule -

A
Gram stain
B
India ink preparation
C
Giemsa stain
D
Methanamine-silver stain
High-Yield Explanation
Ans. is 'b' i.e., India Ink preparation * C. neoformans is best demonstrated in CSF by direct microscopy. The capsule is seen as a clear halo around the yeast cells in unstained wet preparations of CSF mixed with a drop of India ink or nigrosine. Methenamine silver stain would be the best choice for a tissue sample.

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