Least Cardiotoxic anaesthetic agent

B i.e. Isoflurane Isoflurane increases ICT but less than halothane & enflurane; which can be reversed by hyperventilation. So isoflurane is a preferable agent in raised ICT. Isoflurane is anaesthesia of choice (AOC) for neurosurgical procedureQ as it does not increase cerebral blood flow & CSF pressure. Of various inhalation agents available, isoflurane has the advantage of providing stability of cardiac rhythm & lack of sensitizention of the hea to exogenous & endogenous adrenalineQ. In coronary aery disease isoflurane should be avoided Wt coronary steel phenomenonQ. In ischemia of cardiac muscle selective vasodialation of vessels of Ischemic zone and maintained tone of non ischemic zone //t selective increase of blood supply to ischemic areas. But in coronary steal phenomenon (Isoflurane & Dipyridomole) there is dialation of vessels of non ischemic zone also so there is decrease of flow in ischemic zone.Q That is why isoflurane is avoided in ischemic hea disease. In Myocardial Infarction operation should be with held for 6 monthsQ. Goldman Index is for cardiac risk factor and when it is > 13 it is associated with poor prognosis. In hypeension, halothane is AOC (for hypotensive surgery) In hypovolumia, Light G.A. (preferably Ether and Cyclopropane) with IPPV is method of choice Isoflurane increases ICT but less than halothane & enflurane; which can be reversed by hyperventilation. So isoflurane is a preferable agent in raised ICT. Isoflurane is anaesthesia of choice (AOC) for neurosurgical procedureQ as it does not increase cerebral blood flow & CSF pressure. Of various inhalation agents available, isoflurane has the advantage of providing stability of cardiac rhythm & lack of sensitizention of the hea to exogenous & endogenous adrenalineQ. In coronary aery disease isoflurane should be avoided Wt coronary steel phenomenonQ. In ischemia of cardiac muscle selective vasodialation of vessels of Ischemic zone and maintained tone of non ischemic zone //t selective increase of blood supply to ischemic areas. But in coronary steal phenomenon (Isoflurane & Dipyridomole) there is dialation of vessels of non ischemic zone also so there is decrease of flow in ischemic zone.Q That is why isoflurane is avoided in ischemic hea disease. In Myocardial Infarction operation should be with held for 6 monthsQ. Goldman Index is for cardiac risk factor and when it is > 13 it is associated with poor prognosis. In hypeension, halothane is AOC (for hypotensive surgery) In hypovolumia, Light G.A. (preferably Ether and Cyclopropane) with IPPV is method of choice