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Pathology Free Radical Injury 784ca9f0

Which of the following is a free radical scavenging enzyme?

A
Myeloperoxidase
B
Glutathione peroxidase
C
NADPH oxidase
D
Protease
High-Yield Explanation
Elimination of free radical occur multiple mechanism:- 1.Antioxidant: (Glutathione and vitamin A, C, E) 2.Enzymes:- (i) Superoxide dismutase(mitochondria) O2-H2O (ii) Glutathione peroxidase (mitochondria) (iii) Catalase (Peroxisome): H2O2-O2 and H2O (glutathione independent). 3. Metal Carrier protein (Transferrin/Ceruloplasmin). Destruction of phagocytose material:- Oxygen dependent killing is most effective mechanism.

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