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Anaesthesia Neuromuscular Blocker 77afe795

Which by product of vecuronium is associated with peripheral neuropathy on prolonged infusion-

A
3- hydroxy vecuronium
B
17-hydroxy vecuronium
C
3, 17 (OH2) metabolite
D
All
High-Yield Explanation
The most potent byproduct of vecuronium is 3-hydroxy vecuronium, with approximately 60% of the activity of vecuronium, is excreted by the kidney and may be responsible for prolonged paralysis. Vecuronium - 1. It is unstable in solution and, for this reason, is supplied as a lyophilized powder that must be dissolved in sterile water before its use. 2. Both hepatic and renal metabolism. 3. To be used cautiously in pretesting liver & renal dysfunction 4. Neonate, obstetric, geriatric and obese prolonged duration of action is observed.

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