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Medicine General 7770e14c

Pheochromocytoma predominantly secretes which hormone: September 2007

A
Serotonin
B
Epinephrine
C
Nor-epinephrine
D
Dopamine
High-Yield Explanation
Ans. C: Nor-epinephrine Relative catecholamine levels also differ in pheochromocytomas. Most pheochromocytomas secrete norepinephrine predominantly, whereas secretions from the normal adrenal medulla are composed of roughly 85% epinephrine. Familial pheochromocytomas are an exception because they secrete large amounts of epinephrine. Thus, the clinical manifestations of a familial pheochromocytoma differ from those of a sporadic pheochromocytoma.

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