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Biochemistry General 7718f56b

Function of LCAT is:

A
Helps in cholesterol synthesis
B
Conves cholesterol to cholesterol ester
C
Helps in formation of chylomicrons
D
All of the above
High-Yield Explanation
The cholesterol (cholesteryl) ester forms an integral pa of HDLThe cholesterol from the peripheral tissues is trapped in HDL by a reaction catalyzed by LCATLecithin-cholesterol acyltransferase/ LCAT/ Phosphatidylcholine-sterol 0-acyltransferaseIt conves free cholesterol into cholesteryl ester (a more hydrophobic form of cholesterol)Which is then sequestered into the core of a lipoprotein paicle, eventually making the newly synthesized HDL spherical and forcing the reaction to become unidirectional since the paicles are removed from the surface.The enzyme is bound to high-density lipoproteins (HDLs) and low-density lipoproteins in the blood plasma

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