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Gynaecology & Obstetrics Gestational Trophoblastic Disease 7668f64c

Possible cause of choriocarcinoma after hydatidiform mole is all except:

A
Rising hCG
B
More Theca lutein cysts
C
Increase uterus size
D
Sub urethral nodule
High-Yield Explanation
Ans. is b, i.e. More theca lutein cystsSuburethral Nodule indicates metastases choriocarcinoma. All others are very well seen in the conversion of a complete hydatidiform mole into choriocarcinoma except more theca lutein cyst.It is not the number of cyst but size of cyst (>= 6 cms) which indicate neoplastic \conversion.Suburethral nodule may be a manifestation of vaginal metastasis from choriocarcinoma.Metastatic choriocarcinoma is however seen in only about 4% of patients after evacuation of a complete mole and vaginal metastasis that may present with suburethral nodule occur in only 30% of patients with such metastatic disease. Hence it is an unusual indicator.Raised b-hCG level present in choriocarcinoma.

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