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Surgery G.I.T 7655f703

Gardener&;s syndrome is a rare hereditary disorder involving the colon. It is characterized by

A
Polyposis colon, Cancer thyroid, skin tumours
B
Polyposis is jejunum, pituaitary adenoma and skin tumours
C
Polyposis colon, osteomas, epidermal inclusion cysts and fibrous tumours in the skin
D
Polyposis of gastrointestinal tract, cholangiocarcinoma and skin tumours
High-Yield Explanation
.GARDNER'S SYNDROME * It is commonly associated with FAP - 10%. * Presents with bone, skin, soft tissue and dental abnormalities. Jaw osteomas are very common. Other features are epidermoid cysts (50%), exostoses, fibromas, lipomas. * Associated with desmoid tumours seen in the scar, abdomen, intraabdominal region and mesenteric fibromatosis. * Congenital hyperophy of pigment layer of retina (seen as pigment spots)--commonly seen. * Often associated with MEN IIb syndrome. ref:SRB&;s manual of surgery,ed 3,pg no 834

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