Granulomatous inflammatory reaction is caused by all, except -

Ans. is 'd' i.e., Mycoplasma Granulomatous inflammation It is a distinctive pattern of chronic inflammatory reaction characterized by focal accumulations of activated macrophages, which often develop an epithelial - like appearance, i.e., epitheloid macrophages and multinucleated giant cells. It is characterized by formation ofgranuloma. Granuloma may be : ? 1. Immunological (Hypersensitivity) granuloma : ? It is due to lymphocytic-mediated response to an antigen. 2. Nonimmune granuloma It does not require antigen specific lymphocytes. It usually forms in response to poorly digestable substances, e.g., Silica. Immune granulomas Bacterial Fungal Helminthic Others Tuberculosis o Histoplasma o Schistosomiosis o Sarcoidosis Leprosy o Blastomycosis o Trichiniasis o Crohn's disease Brucellosis o Coccidomycosis o Filariasis o Wegener's granulomatesis Syphilis o Capillariasis o R.A. Salmonellosis o Giant cell aeritis Listeriosis o Primary biliary cirrhosis Q fever o Hodgkins disease Cat scratch dis. o Berylliosis Yersinia sp. Non immune granuloma Foreign body type granuloma Silica granulomatosis Foreign body type pneumonia Remember Amongst the above granulomatous conditions, Caseous necrosis, (Caseating granuloma) is seen in ? 1. T.B. 3. Histoplasma 2. Syphilis 4. Coccidiomycosis In TB both caseating and noncaseating granuloma occurs.