Which of the following is the investigation of choice for invasive amebiasis?
High-Yield Explanation
Among the options given in the question ELISA is the investigation of choice in invasive amoebiasis. It has a sensitivity and specificity of 100 and 60%. But PCR assay for DNA in stool samples is currently most sensitive and specific method for identifying E.histolytica infection. Ref: Harrisons Internal Medicine, 18th Edition, Chapter 209 ; Current Medical Diagnosis and Treatment 2012, Chapter 35