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Medicine Oesophagus 7604ea33

All except are features plummer vinson syndrome: (Repeat)

A
Hypertrophy of oral mucosa
B
Dysphagia
C
Glossitis
D
Iron deficiency anemia
High-Yield Explanation
Ans: A (Hypertrophy of oral mucosa) Ref: Harrison's Principles of Internal Medicine, 18edExplanation:Plummer-Vinson syndrome (PVS)Also called Paterson-Brown-Kelly syndrome or sideropenic dysphagiaIt is PremalignantPresents as a triad ofDysphagiaEsophageal websIron deficiency anemiaIt most usually occurs in postmenopausal women.Clinical featuresBurning sensation with the tongue and oral mucosaAtrophy of lingual papillae produces a smooth, shiny, red dorsum of the tongue.DysphagiaPainWeaknessOdynophagiaAtrophic glossitisAngular stomatitisThe condition is associated with koilonvchia, glossitis, cheilitis, and splenomegaly.Hemogram - Microcytic hypochromic anemia suggestive of Iron deficiencyIncreased risk of squamous cell carcinoma of Esophagus

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