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Pharmacology Anesthesia 75f41502

Suxamethonium is

A
Non depolarizing muscle relaxant
B
Direct acting muscle relaxant
C
Depolarising muscle relaxant
D
All of the above
High-Yield Explanation
Depolarizing neuromuscular blockers Succinylcholine (SCh., Suxamethonium), Side effects:- Muscle fasciculations and soreness, changes in BP and HR, arrhythmias, histamine release and K+ efflux from muscles causing hyperkalaemia. Uses:- SCh is the most commonly used muscle relaxant for passing tracheal tube. It induces rapid, complete and predictable paralysis with spontaneous recovery in ~5 min. Excellent intubating condition viz. relaxed jaw, vocal cords apa and immobile with no diaphragmatic movements, is obtained within 1-1.5 min. Avoided/contraindication:- It should be avoided in younger children unless absolutely necessary, because risk of hyperkalaemia and cardiac arrhythmia is higher. Risk of regurgita- tion and aspiration of gastric contents is increased by SCh in GERD patients and in the obese, especially if stomach is full. Ref:- kd tripathi; pg num:-347,353

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