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Pediatrics Gastrointestinal tract 75acc395

Conjugated bilirubin is increased in ?

A
Rotor syndrome
B
Gilbe's syndrome
C
Crigler Najjar syndrome 1
D
Crigler Najjar syndrome 2
High-Yield Explanation
crigler najjar syndrome-1:defect in conjugation,so unconjugated bilirubin level increases to more than 20mg/dl crigler najjar syndrome-ll:second stage of conjugation is defective Gilbe&;ssyndrome:defect in the uptake of bilirubin by liver. Rotor&;s syndrome:bilirubin excretion is defective, but there is no staining of liver. TEXTBOOK OF BIOCHEMISTRY,D.M.VASUDEVAN,PG NO:251,252,6th edition

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