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Medicine General 756cc517

Central nervous system manifestation in chronic renal failure are result of all of the following, except:

A
Hyperosmolarity
B
Hypocalcemia
C
Acidosis
D
Hyponatremia
High-Yield Explanation
Answer is B (Hypocalcemia): 'The total plasma calcium concentration in CRF patient is significantly low. Patient with chronic renal disease tolerate the hypocakemia quite ;veil and rarely is a patient symptomatic from the decreased calcium concentration. This may be paly due to concomitant acidosis.' - Harrison Hyponatremia, acidosis and hyper osmolarity can lead to various CNS manifestation as lethargy, altered mentation, seizure, coma, and paralysis etc.

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