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Pharmacology Anesthesia 756632b1

True statement about sevoflurane is:

A
It is nephrotoxic at high doses
B
It has maximum risk of causing convulsions
C
It is cardiostable
D
It can cause fulminant hepatitis
High-Yield Explanation
Sevoflurane is chemically unstable and is degraded by carbon dioxide absorbers to a metabolite taut can cause nephrotoxicity. Sevoflurane undergoes bio transformation in the liver to release fluoride ions which can cause nephrotoxicity. Sevoflurane doesn't cause fulminating hepatitis nor convulsions. From padmaja 4th edition Page no 193

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