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Biochemistry Glycogen Metabolism and Glycogen Storage 75486946

Glycogen phosphorylase coenzyme associated is?

A
Thiamine pyrophosphate
B
Tetrahydrofolate
C
Flavin mononuleotide
D
Pyridoxal phosphate
High-Yield Explanation
ANSWER: (D) Pyridoxal phosphateREF: Lehninger Principles of Biochemistry 4th edition page 562Pyridoxal phosphate is an essential cofactor in the glycogen phosphorylase reaction; itsphosphate group acts as a general acid catalyst, promoting attack by Pi on the glycosidic bond. (This is an unusual role for this cofactor; its more typical role is as a cofactor in amino acid metabolism)Flavin mononucleotide (FMN), or riboflavin-5'-phosphate, is a biomolecule produced from riboflavin (vitamin B2) by the enzyme riboflavin kinase and functions as prosthetic group of various oxidoreductases including NADH dehydrogenase as well as cofactor in biological blue- light photo receptors

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