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Physiology General physiology 751fcc6c

All of the following are true about mitochondria except

A
Evolved from aerobic bacteria engulfed by eukaryotic cells
B
Have role in regulation of apoptosis
C
Have their own genome
D
Mitochondrial diseases are paternal in inheritance
High-Yield Explanation
"Over a billion years ago, aerobic bacteria were engulfed by eukaryotic cells and evolved into mitochondria, providing the eukaryotic cells with the ability to form the energy-rich compound ATP by oxidative phosphorylation. Mitochondria perform other functions, including a role in the regulation of apoptosis (programmed cell death), but oxidative phosphorylation is the most crucial." Consistent with their origin from aerobic bacteria, the mitochondria have their own genome. As a zygote, mitochondria are derived from the ovum, their inheritance is maternal. This maternal inheritance has been used as a tool to track evolutionary descent. Mitochondria have an ineffective DNA repair system, and the mutation rate for mitochondrial DNA is over 10 times the rate of nuclear DNA.Reference: Ganong's Review of Medical Physiology; 25th edition; Page no: 36

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