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Pediatrics Genetics And Genetic Disorders 7504a38c

Genomic imprinting is seen in:

A
Prader Willi syndrome
B
Marfan syndrome
C
Down syndrome
D
Osteogenesis imperfect
High-Yield Explanation
a. Prader-Willi syndrome(Ref: Nelson's 20/e p 624-626, Ghai 8/e p 637)Genomic imprinting occurs when the phenotypic expression of a gene depends on the parent of originClassic examples: Prader-Willi syndromeQ and Angelman syndromeQ, Beckwith-Wiedemann syndromeQ, Russell- Silver syndromeQ, pseudohypoparathyroidism and neonatal diabetes.

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