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Pharmacology General 744d4a76

All of the following are criteria for high risk of deveoping chloroquine retinopathy except

A
Duration of use > 5 years
B
Seen at a dose of >250mg/d or >3mg/kg
C
>480g total dose
D
Presence of renal failure
High-Yield Explanation
Criteria of High Risk for Developing Chloroquine Retinopathy Dosage > 6.5 mg/kg hydroxychloroquine or > 3 mg/kg chloroquine Duration of Use > 5 years High fat level (unless dosage is appropriately low) Presence of renal/liver disease Presence of concomitant retinal disease Age > 60 years Previously cumulative dose of > 1g/Kg was considered as a high risk factor which is now not considered.

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